What is the significance of the elastic tissue in the lungs




















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They found that new elastin synthesis was initiated in moderately diseased specimens. The researchers did a second study using 10 lungs from end-stage COPD patients who had undergone transplants.

Again, they found the greatest amount of elastin gene expression in the moderately diseased areas of the lungs, Woods said. There was no variability in elastin levels within the control lungs. Further, the team found that the increase in elastin expression occurred on the alveolar walls, the same area where elastin occurs during the lung's development in children.

This shows the lung is attempting to repair the elastic fibers in end-stage emphysema, the authors concluded. The American Physiological Society was founded in to foster basic and applied bioscience. The Bethesda, Maryland-based society has 10, members and publishes 14 peer-reviewed journals containing almost 4, articles annually.

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The authors would like to acknowledge the financial support of the Royal British Legion. The authors would also like to acknowledge: the assistance from the Weinberg group, in particular Dr. Emma Bailey and Dr. Eleni Bazigou for supplying the lung tissue for these experiments; the assistance of Dr. Ben Almquist on checking the statistics; and the helpful discussions with Dr.

Maria N. Charalambides during this project. You can also search for this author in PubMed Google Scholar. All authors contributed towards writing and reviewing the manuscript. This work is licensed under a Creative Commons Attribution 4. Reprints and Permissions. Andrikakou, P. Sci Rep 6, Download citation. Received : 25 August Accepted : 17 October Published : 07 November



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